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Preclinical Research Intern - 12 months

London
Full-time
Intern / Student

Your mission

The preclinical intern will support senior MeiraGTx scientists in undertaking experiments to develop AAV-based gene therapy treatments for neurodegenerative and ocular diseases such as ALS and AMD.

Job Description

Major Activities and Responsibilities

Cell culture
  • Work under sterile conditions appropriate for cell culture.
  • Grow and maintain induced pluripotent stem cells (iPSCs).
  • Grow iPSC-derived cells such as neurons, retinal pigment epithelium, and myotubes.
Perform experiments
  • Design and implement experimental protocols.
  • Collect and analyse data.
Presentation of data
  • Report results to team at regular meetings.
  • Prepare posters or talks to share projects with others.

Key Job Competencies

  • Lab skills: sterile technique, pipetting skills, familiarity with lab techniques such as PCR and Western blots.
  • Problem solving.
  • Ability to closely cooperate with supervisor and other team members.

Job Background

  • University degree in a science field.
  • Molecular biology lab experience.
  • Cell culture experience preferred.

About us

MeiraGTx is a clinical-stage gene therapy company focused on developing potentially curative treatments for patients living with serious diseases. We currently have six programs in clinical development including three ocular indications, a salivary gland condition, and a Parkinson’s disease program. Our initial focus on diseases of the eye, salivary gland and central nervous system is based on the significant unmet medical need coupled with the high potential gene therapy has to provide meaningful clinical benefit in these areas. With headquarters in New York and London, our global footprint provides us the opportunity to partner with leading institutions around the world, allowing us to deepen our understanding of diseases and their progression.

Our team was built with deep expertise in gene therapy development, allowing us to efficiently advance our programs from preclinical to clinical development. Our core capabilities in viral vector design and optimization and gene therapy manufacturing give us a differentiated approach to developing gene therapies. Additionally, we are developing proprietary technology to potentially enable innovative gene therapy treatments whose expression can be turned on and off with an easily administered small molecule. We believe temporal control of gene therapy products has the potential to transform the gene therapy landscape.

Our state-of-the-art manufacturing facility, completed in early 2018, was designed to meet global regulatory requirements, including the current good manufacturing practices (cGMP) required by the Medicines and Healthcare products Regulatory Agency (MHRA) in the UK and the U.S. Food and Drug Administration (FDA). The 29,000-square foot facility has the flexibility and capacity to produce sufficient product for all our clinical trials and will scale to commercial capacity.