Facilities/Maintenance Manager

Permanent employee, Full-time · London

Your mission
The role is required to manage and lead the multi Discipline on site facilities and Maintenance team. The role will report to the Director of Engineering Ireland &UK.
Job Description
Responsibilities:

  • Fulfil the role of Manager for Maintenance, Facilities and Utilities resources.  
  • Ensure the various maintenance and operations related tasks are effectively performed.  
  • Ensure that objectives are effectively achieved, consistent with requirements to ensure compliance, safety, and reliable supply to our customers.  
  • Coordinate and execute Maintenance activities, preventative maintenance, calibration. 
  • Support equipment improvement projects, to ensure optimum equipment uptime and target outputs.  
  • Ensure that all Planned Maintenance and Calibration activities are completed on plan as per the PM/Calibration schedule.  
  • Collaborate with Quality, EHS, Manufacturing Operations, in completion of tasks to ensure best practice outputs  
  • Coordinate scheduled, tasks and resources, including vendor management, communications. 
  • Support training, project work, audit/inspection duties etc.  
  • Manage equipment flow, through maintenance cycles.  
  • Review  and post execution approval of preventative maintenance, corrective maintenance. and calibration work orders. Approval of change controls, CAPA's etc  
  • Ensure process equipment is maintained including preventative maintenance.  
  • Troubleshooting and repairs to ensure continuous, reliable, and repeatable operation of equipment.
  • Effectively manage and schedule equipment shutdowns, ensuring resources are available, thereby minimizing downtown.  
  • Ensure effective participation in writing/revising/ rolling out accurate, task lists, technical engineering reports, training documents and maintenance procedures for various systems.  
  • Ensure equipment reliability and performance by ensuring root cause analysis is performed and subsequent recommendations and improvement changes throughout processes are implemented.
  • Troubleshoot equipment problems, identify need for new equipment and/or modifications to existing equipment to optimize throughput and reduce process cycle      times.
  • Drive change through Change control system in line with deadlines  
  • Leadership activities including selection, development, coaching of the maintenance/facilities engineering team.
  • Development in line with role. Develop and maintain training programmes.  
  • Participate      in on-call rota and callouts when required.  
  • Ensure own work      complies with GMP, Data integrity and Good Documentation Practice (GDP)      and is undertaken in accordance with applicable quality documents e.g SOP’s, BMR’s, Protocols, Guidance’s etc.  
  • Ensure own training in undertaken in a timely and GMP compliant manner before the task is undertaken.
  • Ensure own KPI’s, plans, targets and objectives are effectively tracked, monitored, and achieved in accordance with timelines. Aid in maintaining QA Operations Team KPIs.

Requirements:

  • Qualified to Degree level in an engineering Discipline.  
  • Min of 10 years of experience in manufacturing/Facilities maintenance.  
  • Experience implementing Lean Principals across maintenance department.  
  • Strong communicator with Manager/Team Lead experience.  
  • Understanding of Reliability centred maintenance.  
  • Knowledge of Building management systems, Environmental Monitoring systems and CMMS  
  • Technical problem-solving leadership - structured analysis & reporting  
  • Experience of best practice maintenance, life cycle management and asset care.  
  • Strong Health and Safety awareness leadership.  
  • Experience of best practice maintenance, life cycle management and asset care.  
  • Ability to manage Budgets. 
About us

MeiraGTx is a clinical-stage gene therapy company focused on developing potentially curative treatments for patients living with serious diseases. We currently have six programs in clinical development including three ocular indications, a salivary gland condition, and a Parkinson’s disease program. Our initial focus on diseases of the eye, salivary gland and central nervous system is based on the significant unmet medical need coupled with the high potential gene therapy has to provide meaningful clinical benefit in these areas. With headquarters in New York and London, our global footprint provides us the opportunity to partner with leading institutions around the world, allowing us to deepen our understanding of diseases and their progression.

Our team was built with deep expertise in gene therapy development, allowing us to efficiently advance our programs from preclinical to clinical development. Our core capabilities in viral vector design and optimization and gene therapy manufacturing give us a differentiated approach to developing gene therapies. Additionally, we are developing proprietary technology to potentially enable innovative gene therapy treatments whose expression can be turned on and off with an easily administered small molecule. We believe temporal control of gene therapy products has the potential to transform the gene therapy landscape.

Our state-of-the-art manufacturing facility, completed in early 2018, was designed to meet global regulatory requirements, including the current good manufacturing practices (cGMP) required by the Medicines and Healthcare products Regulatory Agency (MHRA) in the UK and the U.S. Food and Drug Administration (FDA). The 29,000-square foot facility has the flexibility and capacity to produce sufficient product for all our clinical trials and will scale to commercial capacity.

We are looking forward to hearing from you!
Thank you for your interest in MeiraGTx. Please fill out the following short form. Should you have difficulties with the upload of your data, please send an email to talent@meiragtx.com
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